Kev tswj cov roj roj ntxhia cov ntsiab lus hauv cov vitamin E: Txoj kev thiab cov nyom

Kev tswj cov roj roj ntxhia cov ntsiab lus hauv cov vitamin E: Txoj kev thiab cov nyom

 

Ntuj Vitamin E (sib xyaw ntawm tocopherols thiab tocottrienols) yog cov antioxidant dav thiab antioxidant dav siv hauv cov zaub mov, cov tshuaj, thiab tshuaj pleev ib ce. Txawm li cas los xij, thaum lub sij hawm nws tsim khoom los ntawm cov ntxhia roj hydrocarbons (moh), suav nrog cov roj ntsha tsis zoo (MAHH), ua cov ntxhiab tsw qab. Ntev ntev raug rau moh tau txuas rau kev ua qe ua haujlwm thiab muaj kev lom zem. Kab lus no sib tham txog kev tswj cov roj roj ntxhia cov ntsiab lus hauv cov vitamin e, hais txog kev siv tshuab ua kom huv.

 

Qhov chaw thiab txaus ntshai ntawm cov roj ntxhia paug
Cov roj ntxhia, muab tau los ntawm roj av, feem ntau infiltrate natural vitamin E dhau cov roj nyoos (piv txwv li zaub roj deodorizer distillates), kev ua khoom siv, lossis ntim khoom. Mosh thiab Mau-ees, tshwj xeeb rau cov neeg nrog Carbon Chains C10-C50, yog hais txog lawv cov nqaij mos thiab tsis paub meej txog cov teebmeem ntev. Cov European Union (EU) tau txo kev txwv rau moh hauv cov khoom noj khoom haus khoom noj ntxiv, xav tau Mosh<1,000 ppm and MOAH below detection thresholds.

Cov Tswv Yim Txheem Phaj Tseem Ceeb

1. Chromatographic sib cais raws li polarity sib txawv
Polarity Disparity ntawm cov roj ntxhia (tsis muaj zog tsis yog (tsis muaj zog tshaj plaws
- Ib-theem cov chromatography: tsis muaj zog polrvents (piv txwv li, tus kab mob n-aws Xaiv elution impurities. Silica gel, ua haujlwm carbon, lossis ion-sib pauv ua haujlwm pab raws li nyob hauv theem. Cov qauv no txo ​​cov ntxhia roj cov roj nyob rau<10 ppm (MOSH <9 ppm, MOAH <1 ppm) with >95% Vitamin e rov qab.
- Ob-theem chromatography: ib nrab kem ntxiv kho cov khoom. Piv txwv li, Pre-kem adsorption tshem tawm feem ntau moshh / Mijah, thaum lub sij hawm}}}}}}} 8}} pp moah).

2. Molecular distillation
High-temperature (180°C) and low-pressure (1 Pa) molecular distillation effectively separates vitamin E from low-volatility impurities like mineral oils. Combined with chromatographic methods, this boosts purity to >97%.

3. Saponification thiab Acid Ntxuav
Saponification nrog alkaline cov kev daws converts cov fatty acids dawb rau hauv xab npum, uas ntxiab ntxhia roj. Tom ntej acid ntxuav thiab lub cev qhuav dej tawm los ua kom huv vitamin e roj. Txoj kev no yog qhov yooj yim thiab siv tau zoo tab sis yuav xav tau cov kauj ruam ntxiv kom khaws cov vitamin e kev ruaj khov.

 

Kev ntsuas cov tswv yim rau kev tswj kom zoo
- Nyias-txheej chromatography (TLC): Txaus siab rau kev kuaj xyuas thaum cov kauj ruam chromatographic los saib cov vitamin E Bandurity tshem tawm.
- Kua / Roj Chromatography (LC / GC): Kev Tshawb Xyuas QuanSitive ua raws li EU cov qauv, kuaj pom Mosh / Moah rau qib-lab-lab-lab-lab-billion.

 

Cov kev sib tw thiab yav tom ntej
1. Kev nyuaj siab: Ntau kauj ruam purification (piv txwv li, ob-theem chromatography) nce cov nqi thiab sijhawm.
2. Scalability: Kev hloov kho muaj kev hloov kho yuav tsum tau ua kom cov kuab rov qab thiab kem dua tshiab.
3. Tawm cov thev naus laus zis: cov kuab tshuaj ntsuab, piv txwv li cov resins), thiab cov kev lim nyiaj ua kom muaj kev ua tau zoo thiab ntev.

 

Kev tswj cov roj roj ntxhia cov ntsiab lus hauv cov vitamin e xav tau kev sib xyaw ua ke ntawm chromatographic sib cais, molecular distillation, thiab kev ntsuas nruj. Raws li cov kev cai thoob ntiaj teb ua kom nruj, txhim kho cov thev naus laus zis thev naus laus zis yuav tseem ceeb rau kev nyab xeeb cov khoom muaj kev nyab xeeb thiab kev lag luam tau txais.

 

Ntawv Sawv cev
[1] CN201410147994.x; CN201210554975.x
[2] CN201711191370.8
[3] CN202010204287.x
[4] CN107903236A
[6] CN201711191370.8

* (Nco tseg: kom cov ncauj lus kom ntxaws thiab cov ntaub ntawv sim, xa mus rau cov ntawv sau ua patents thiab cov ntaub ntawv.)